Who We Are: Xenon Pharmaceuticals (NASDAQ:XENE) is a neuroscience-focused biopharmaceutical company committed to discovering, developing, and commercializing innovative therapeutics to improve the lives of people living with neurological and psychiatric disorders. We are looking for great people who thrive in a respectful, collaborative, inclusive, and productive culture to join the Xenon team. What We Do: We are advancing an exciting product pipeline to address indications with high unmet medical need, including epilepsy and depression. Our flagship azetukalner program represents the most advanced potassium channel modulator in clinical development for multiple indications. Building upon the positive results and compelling data from our Phase 2b “X-TOLE” study in adult patients with focal epilepsy, our Phase 3 epilepsy program includes multiple clinical trials evaluating azetukalner in patients with focal onset seizures and primary generalized tonic-clonic seizures. In 2024, we are planning to initiate a Phase 3 azetukalner program in major depressive disorder, based on topline data from our Phase 2 “X-NOVA” clinical trial. In addition, we are proud of the leading-edge science coming out of our discovery labs, including early-stage research programs that leverage our extensive ion channel expertise and drug discovery capabilities to identify validated drug targets and develop new product candidates. Backed by a strong balance sheet to support our growth plans, we continue to build a fully integrated, premier neuroscience company with strong discovery, clinical development, corporate, and commercial operations. About the Role: We are seeking a Director/Senior Director, Bioanalytical to join our team. This role will lead our Bioanalytical team. As such the position will be responsible for managing a team, overseeing our ADME assays, and completing bio-analytical data on in vivo samples from studies. In addition, the successful candidate will be involved in collaborating and guiding scientific plans and strategies to successfully develop compounds to become development track candidates (DTCs). This position reports to the Executive Vice President, Drug Discovery and will be based out of Vancouver, BC, Canada. The level of the position will be commensurate with the candidate’s education and industry experience. Relocation and immigration support will be provided, if required. This role is a hybrid position, requiring a minimum of 3-4 days per week in the office. RESPONSIBILITIES: Lead and manage the Bioanalytical team. Ensure state-of-the-art Bioanalytical methods are developed and utilized; support the group in all scientific and technical aspects related to ADME and bio-analytical activities ensuring that a consistent high standard of science and quality are applied to the design and conduct of all ADME and Bio-analytical studies. Collaborate with Discovery colleagues to develop and implement ADME and Bioanalytical plans and strategies. Provide scientific expertise to project team leaders in various aspects of ADME and DMPK. Contribute to the planning, decision and execution process of new discovery strategies and projects. Lead and direct program or project activities through assigned resources and/or with CROs. Participate and advise in the selection of CRO's dealing with ADME and bioanalytical applications to projects. Contribute to the Discovery management team; ensure activities and decisions are carried through the Bioanalytical department. Contribute to the compilation of ADME and PK data sections of regulatory and non-regulatory documentation for assigned projects. Design and implement a learning and development program for the team to support continuous learning and employee engagement. Critically evaluate scientific literature, integrate new information into existing knowledge base, and identify gaps for new investigation. Regularly contribute to scientific literature and presentations at conferences. Independently write, coordinate and publish to scientific literature and present at conferences. Keep up to date and detailed records of experiments and data analysis within an Electronic Lab Notebook system. Ensure experiments are counter-signed on a monthly basis. Ensure the proper use and maintenance of all ADME and bio­analytical equipment. Ensure the laboratory environment is safe and well-organized; follow and keep up to date with Health & Safety policies. Develop and propose short- and long-term objectives for the function in accordance with overall Company strategies and plans. Plan and manage budget proposals and approved budgets in accordance with the Company’s strategic and operating plans and Finance policies, Recruit, lead, direct, develop, coach and evaluate direct reports, if any, in accordance with the Company’s Human Resource policies and practices. Act in accordance with Company policies, including, for example, the Code of Business Conduct and Ethics and ensure policies are understood and followed by direct reports, if any. Some international travel may be required. Other duties as assigned. QUALIFICATIONS: Master’s or Bachelor's degree in bioanalytical chemistry, biochemistry, chemistry, mass spectroscopy, or related field; a minimum of 10 years of relevant experience leading Bioanalytical teams and resources Strong expertise in quantitative Mass Spectrometry applications for analytical chemistry Proven experience in leading and managing scientific teams; acts as a collaborator and “guide” within Discovery and for early-stage development colleagues Experience compiling ADME and PK data sections for regulatory and non-regulatory documentation Strong communication skills and ability to effectively collaborate with cross-functional teams and influence the decision-making process Excellent verbal communication and presentation skills with the ability to write clearly and concisely The base salary range for this role is $175,000 to $255,000 CAD; we will consider above this range for exceptional candidates. Base salary is determined by a combination of factors including, but not limited to, education and other qualifications, years of relevant experience, and internal equity. Our Total Rewards program includes base salary, target bonus, and stock options, as well as a full range of benefits including medical, dental, vision, short-& long-term disability, accidental death & dismemberment, and life insurance programs, Employee Assistance Program, travel insurance, and retirement savings programs with company matching contributions. Xenon encourages time to rest and re-charge through vacation, personal days, sick days, and an end-of-year company shutdown. Xenon highly values employee development and has an expanding Training, Learning & Development program, including a Tuition Assistance program for advanced degrees. As part of our hiring process, Xenon conducts background checks for finalist candidates. The types of checks conducted will vary depending on the relevance to the position. US positions only: Xenon Pharmaceuticals USA Inc. participates in the E-Verify program in all states in which we hire. Learn more about the E-Verify program here. To apply for this position, click Apply Now to complete the application. We thank all applicants for their interest; however, due to the volume of applicants, only those chosen for interview will be contacted.