We are seeking a strategic and hands-on Head, Manufacturing and Facility
Operations to join Aspect’s Technical Operations team. Reporting to the SVP,
Technical Operations, you will oversee our facilities, lab operations, safety,
and manufacturing operations, including aseptic manufacturing to support
GMP-compliant production. This is a mission-critical role that will ensure our
physical operations scale effectively to support the development and production
of our bioprinted tissue therapeutic (BTT) programs. As we continue our
transition from research to clinical and commercial readiness, you will play a
key role in optimizing infrastructure, enabling operational excellence, and
fostering a culture of safety, quality, and accountability across our labs and
manufacturing environments, with a focus on enabling clinical-grade production
of our bioprinted tissue therapeutics.
Responsibilities
- Develop and execute Aspect’s manufacturing operations strategy in alignment
with organizational goals and program timelines.
- Oversee aseptic manufacturing operations, including cleanroom controls,
gowning procedures, environmental monitoring, and material/personnel flow to
maintain contamination control and compliance with GMP standards.
- Partner cross-functionally to ensure facilities and manufacturing operations
enable robust execution from discovery through clinical readiness.
- Build, lead, and mentor a high-performing manufacturing operations team,
fostering a culture of continuous improvement, GMP compliance, and
operational excellence.
- Manage lab operations including equipment lifecycle, maintenance programs,
calibration, and inventory management systems.
- Support the implementation of manufacturing best practices, including
documentation systems, materials management, and training protocols.
- Lead day-to-day site operations and long term facilities planning, ensuring
our labs, offices, and production areas are optimized, safe, and compliant.
- Oversee the installation, qualification (IQ/OQ/PQ), maintenance, and
calibration of critical manufacturing equipment, ensuring optimal
performance, data integrity, and adherence to GMP standards and asset
lifecycle management.
- Develop and maintain robust preventative maintenance programs for
manufacturing facilities and equipment, ensuring compliance with GMP
requirements and managing critical building systems.
- Collaborate with senior leadership to assess and implement facility expansion
plans in line with company growth and program needs.
- Champion a proactive safety culture and manage comprehensive safety programs,
including biosafety, chemical safety, incident reporting, and emergency
response.
- Ensure compliance with all relevant occupational, environmental, and
biosafety regulations.
- Manage vendor relationships for services, utilities, and facilities
contractors.
Qualifications & Experience
- Education & Experience: Bachelor's or Master’s degree in Life Sciences,
Engineering, or a related field and 10+ years of progressive experience as a
leader within a GMP-regulated biotech, pharmaceutical, or scientific R&D
environment.
- Leadership: Demonstrated success in leading multidisciplinary teams and
managing large-scale operational initiatives in high-growth or strictly
regulated (GMP) settings.
- Regulatory Compliance: Expert understanding and practical application of GMP
principles and guidelines.
- Capital Projects: Proven experience in planning and executing facility
expansions, renovations, and capital improvement projects within a GMP
environment, including understanding of validation requirements.
- Quality Systems: Experience with quality management systems (QMS) and their
application within facilities and lab operations in a GMP setting.
- Collaborative Influencer: You partner cross-functionally with technical,
finance, and leadership teams to align on priorities and deliver results.
- Team Builder: You lead by example, coach high-performing teams, and cultivate
a culture of excellence and accountability.
- Detail-Oriented Executor: You balance strategic vision with rigorous
attention to safety, compliance, and operational detail.
- Proactive & Driven: You thrive in fast-paced, evolving environments and bring
a sense of urgency and ownership to your work.
The hiring range for this role is $155,000 - $200,000, annually. Our pay scales
are based on market data to ensure that compensation is competitive and fair.
Offered salaries will be based on a combination of factors including, but not
limited to, job-related knowledge, skills, education, and experience. For
candidates who exceed role requirements, we are open to exploring above-range
offers. Base salary is just one part of the overall compensation at Aspect, team
members also receive equity, a comprehensive benefits package, and support for
continuous learning and career progression.
Who We Are
Aspect Biosystems is a Canadian biotechnology company creating bioprinted tissue
therapeutics to transform how we treat disease. Our bold team of innovators and
entrepreneurs have joined us from all over the globe to create a new class of
regenerative medicine and work towards a future where our bioprinted tissues are
used to save lives and make people healthier. We are endlessly curious and
wildly passionate about what we do. Every person on our team is a key
contributor to our success and is eager to roll up their sleeves to make a
difference in the ever-changing world of biotech. If you are committed to making
a real impact and accelerating the development of life-changing therapies, we
want to hear from you!
Curious about our current perks and benefits? Learn more here
[https://aspectbiosystems.com/careers].
At Aspect Biosystems, our strength has always been in our diversity. Different
people, thinking differently, unified in creating a world that is better for us
all. We are committed to creating an inclusive environment for everyone on our
team. All aspects of employment — including the decision to hire, promote,
discipline, or terminate — are based on merit, competence, performance, and
business needs. We do not discriminate on the basis of race, colour, religion,
marital status, age, national origin, ancestry, physical or mental disability,
medical condition, pregnancy, genetic information, gender, sexual orientation,
gender identity or expression, veteran status, or any other status protected
under federal, provincial, or local law.
If you're interested in joining our team but don't see a job posting that
matches your experience or background, we encourage you to submit a general
application [https://boards.greenhouse.io/aspectbiosystems/jobs/4009049008] to
be considered for future opportunities!
